Yes there are. There are three episodes which have mocked them.
- The Tale of Scrotie McBoogerballs - Butters was shown to be a fan of the show and is disappointed to see that the book "The Tale of Scrotie McBoogerballs" has caused Morgan Freeman to kill the Kardashians.
- 200 - Though it was for a short time, Kim Kardashian was seen as one of the many celebrities who have been made fun of by South Park.
- The Hobbit - The girls at South Park Elementary are all convinced by Kim Kardashian to photoshop themselves on the internet in order to be accepted. Kim Kardashian, herself does this to herself in order to look pretty, when in reality, she is a Hobbit.